Marijuana painkiller breakthrough

Marijuana painkiller breakthrough:

Marijuana painkiller breakthrough

Marijuana painkiller breakthrough

What is marijuana without the high? Still a very effective painkiller. And now, scientists believe they can harness the drug’s anesthetic action while doing away with its psychedelic effects. In a new paper published in the journal Nature Chemical Biology, Professor Li Zhang and a team of scientists at the U.S. National Institute on Alcohol Abuse and Alcoholism report that THC can potentially be used as a side-effect-free painkiller. Is a new class of “non-psychotropic cannabinoids” on the way? Here’s a brief guide:

What is this breakthrough exactly?
Zhang and his team discovered that tetrahydrocannabinol (more commonly known as THC), the main psychoactive ingredient in cannabis, produces different effects by bonding to different receptors in the brain. Scientists have known for years that THC bonds with a certain receptor to produce the classic disorienting marijuana high. But now researchers have identified precisely where THC targets the nervous system to lessen anxiety and dull pain. Hence, the potential to satisfy medical marijuana’s desire for pure pain relief.

How’d they figure this out?
By experimenting on mice, naturally. Scientists blocked the pain-reducing receptors in the stoned rodents’ brains, then subjected them to a “tail-flick test” — hitting mices’ tails with “focused heat” — and counted how long it took for them to respond. The fact that the mice still felt pain, even when they were dosed with THC, “confirms that the drug’s pain-relief and psychotropic effects can be decoupled,” says Andy Coghlan at The New Scientist.

So… THC pain pills?
Quite possibly. “Soon,” says Annalee Newitz at IO9, “people whose stomachs are too tender for aspirin or ibuprofin may be swallowing THC pills to get rid of headaches.”

Could another result be THC pills that do nothing but get you high?
It’s the question recreational users will be pondering: “Is there a way to create a synthetic form of THC that does nothing but get you high, without all those pesky ‘medicinal’ side-effects?”

 

Source:  THEWEEK.Com

High IQ and drug use

People that use drugs, are generally smarter than their counter parts:

High IQ linked to drug use

High IQ linked to drug use

The “Just Say No” generation was often told by parents and teachers that intelligent people didn’t use drugs.   Turns out, the adults may have been wrong.

A new British study finds children with high IQs are more likely to use drugs as adults than people who score low on IQ tests as children.  The data come from the 1970 British Cohort Study, which has been following thousands of people over decades.  The kids’ IQs were tested at the ages of 5, 10 and 16.  The study also asked about drug use and looked at education and other socioeconomic factors.  Then when participants turned 30, they were asked whether they had used drugs such as marijuana, cocaine and heroin in the past year.

Researchers discovered men with high childhood IQs were up to two times more likely to use illegal drugs than their lower-scoring counterparts.  Girls with high IQs were up to three times more likely to use drugs as adults.  A high IQ is defined as a score between 107 and 158.  An average IQ is 100. The study appears in the Journal of Epidemiology and Community Health.

The lead researcher says he isn’t surprised by the findings.  “Previous research found for the most part people with high IQs lead a healthy life, but that they are more likely to drink to excess as adults,” says James White a psychologist at Cardiff University in the United Kingdom.

It’s not clear why people with high childhood IQs are more likely to use illegal drugs.  “We suspect they may be more open to new experiences and are more sensation seeking,” says White.  In the paper, White and his co-author also mention other studies that find high IQ kids may use drugs because they are bored or to cope with being different.

That seems to ring true for one of my childhood classmates. Tracey Helton Mitchell was one of the smartest kids in my middle school. But, by the time she was in her early 20’s, Tracey was a heroin addict. I found out while flipping channels one sleepless night and stumbled upon the documentary “Black Tar Heroin.”

“I was confident in my abilities but there was a dissonance,” says Tracey, with whom I recently reconnected.  “No matter what I did, what I said, where I went, I was never comfortable with the shell I carried called myself.”

 

Source: CNN.Com