Protein Drug mimic’s food deprivation

A Drug That Can Extend Life as Effectively As Dieting:

A Drug That Can Extend Life as Effectively As Dieting

A Drug That Can Extend Life as Effectively As Dieting

Many studies have shown that rigorous caloric restriction, or strict dieting, can increase longevity dramatically in lifeforms from yeast to humans. But a study released today shows one way to mimic the life-extending effects of food deprivation – using drugs.

A team of researchers in the UK explored the role of a protein known as S6K1, which turns out to play an extraordinary role in aging and age-related disease. When the researchers grew mice lacking the gene to produce S6K1, their mice lived significantly longer (see chart – the red lines are mice without S6K1). They also developed fewer age-related debilitating conditions.

A Drug That Can Extend Life as Effectively As Dieting

Female mice without S6K1 lived slightly longer than their male counterparts, and over 160 days longer than the control group. That means the female mouse lifespan increased by twenty percent.

Mice without S6K1 also lost weight, even if they ate more than ordinary mice. In other words, a substance that could block the expression of S6K1 would trick the body into thinking that you’d gone on a very rigorous diet. And it would make you healthier into an older age. The best part?

In their paper, the researchers conclude:

It might be possible to develop drug treatments that manipulate S6K1 and AMPK to achieve improved overall health in later life. Indeed, short-term rapamycin treatment reduces adiposity in mice, and metformin treatment [often used against type 2 diabetes] extends lifespan in short-lived mice.

This is good news, because often when researchers make discoveries related to longevity there is no immediate pathway to manufacturing a life-extending drug. For all of us who want to stay healthy in old age while still eating sugar and fat once in a while, let’s hope this research team starts testing a drug based on their S6K1 discovery – and soon.

Egyptian Military guarding secret at Giza Pyramid

 

Something Big Is Going On In Giza:

 

Something Big Is Going On At Giza

Something Big Is Going On In Giza

The internet is abuzz with the news about new findings in the Great Pyramid on Egypt’s Giza Plateau. It has been reported that strange markings have been found inside what many of the news reports have been calling a “secret tunnel”. True to form, the news media are either hyperbolizing, or they just plain got the facts wrong. The tunnel hasn’t been a secret for a number of years. The secret has been what is in the tunnel, and where it leads.

hieroglyph-type markings in newly explored tunnel

There is, however, a mystery involved here. The mystery involves some strange hieroglyphic-type markings found in the tunnel. They are done in red paint, and are found on the floor of the tunnel and on the walls. Not accessible to the human frame as yet, the tunnel was explored by a robot rover with a camera mounted on it. Using the remote controlled robot, the archeologists were able to determine the tunnel runs for runs for some distance and ends at what appears to be another door. It is one of four known secret tunnels that lead from the “King’s Chamber” and the “Queen’s Chamber”. The purpose of the tunnels is not known. The first big story on this event is that the hieroglyphic-type markings are yet to be understood. It does seem quite odd that these markings were found in a pyramid that the Egyptologists claim was built by Pharaoh Khufu (an Egyptian), and they can read the hieroglyphs found from his time. Yet, they cannot yet decode these hieroglyphs from inside the very pyramid they say he built. These are symbols that do not apparently fit with the system of writing known to Egyptologists as hieroglyphics. This would seem to raise the possibility that while these markings are a language, they are not Egyptian. Since the tomb of Osiris was found in a “secret” underground tomb just a few yards from the Great Pyramid (the spot marked by the star Deneb in the Cygnus constellation), is it possible the Great Pyramid was built by the Osiris clan and not by Khufu? If so, is it possible the myths about Osiris and his family (Ra, Isis, Thoth, Set) not being from this planet are true? Perhaps those hieroglyphic-type markings are in the language of Osiris. The second great mystery in this event is that it comes on the heels of finding the tomb of Osiris in 2010, and the discovery by NASA satellites of a massive collection of buried pyramids on the Giza Plateau.  When the tomb of Osiris was found, several very odd measures were undertaken almost immediately. Dr. Zahi Hawass (Minister of Antiquities) ordered that a wall be constructed around the pyramid complex. This was, ostensibly, to protect the pyramids from being damaged by the public. It has been reported on various internet sites that the U.S. military was there securing the pyramid complex along with Egyptian military.  And then, there is the question of the NASA satellite imaging of the Giza Plateau. Why? It has been done before. We already had pictures from space of the Pyramids. Why now? Why a NASA satellite?  When you line up the discoveries and events, a very interesting picture begins to emerge.

  • The tomb of Osiris found
  • Sarcophagus of Osiris opened but no concurrent photos of what is inside
  • Dr. Hawass says the sarcophagus was empty
  • The military called in to secure the site
  • The order is given to build a wall around the pyramid complex
  • NASA satellite called upon to do high-tech scan of the site
  • 17 additional pyramids located in satellite scan
  • Hieroglyphic-type markings found in pyramid that hieroglyph experts can’t read yet

Certainly, this line-up of events gives the appearance that something big–very big–has been discovered at the Giza Plateau. Not only is it something big, it is something of military importance. Not only is it of military importance, it is very secret.  The line-up of events listed above is not theoretical, nor speculative. Those are genuine events. Yet, the internet is filled with speculation about what has been discovered. One theory being touted is that they have found a Stargate. Maybe. Maybe not. Critics of the UFO community tend to ridicule all the speculation. But, when all the facts are not on the table then all speculation is valid. In fact, it is inevitable. Oh, by the way, the name of the robot that took the photo above is Djedi, and the team working with it is the Djedi Team. Djedi is the name of an ancient Egyptian magician in the days of Khufu. The “d” and the “j” are pronounced together making the pronunciation of the word to be JEDI. You remember the JEDI Knights of Star Wars fame, right? One thing seems to be certain. Something very big is going on at Giza.