New gene with a key role in obesity

New gene with a key role in obesity:

New gene with a key role in obesity:

New gene with a key role in obesity:

The researchers observed that blocking the expression of TRIP- Br2 gene protects mice against obesity and insulin resistance . The study shows that the gene modulates fat storage by regulating energy expenditure and lipolysis , the process that transforms fat into lipids for energy in the body. If gene expression is blocked , the mice increase in lipolysis and energy expenditure , thereby reducing their obesity.

Obesity is the result of an alteration in the processes regulating the absorption of food and energy production . This altered balance tips toward excessive fat storage. According to researchers, the understanding of the regulation of the factors controlling the storage, movement and the use of an excess of energy in fat cells ( adipocytes ) can lead to the development of therapies for obesity and related conditions such as type 2 diabetes.

In the words of Cristina Mallol , a researcher at the Autonomous University of Barcelona and co – author of the study : ” The protection of mice lacking expression of TRIP- Br2 gene and its selective elevation of visceral fat in humans point to the path future gene therapy to counteract obesity, insulin resistance and excess lipids in the blood “ .

Share Your Thoughts

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s