Silver nanoparticles could block HIV transmission:
According to the Centers for Disease Control and Prevention, 1.1 million people in the U.S. are infected with the human immunodeficiency virus. But new research has detailed the creation of a cream that has proven effective against the transmission of infection in laboratory tests .
Previous research at the University of Texas, in collaboration with the University of Monterrey in Mexico , found that silver nanoparticles may be able to stop the transmission of the human immunodeficiency virus (HIV) .
Now, the research team used the results to create a vaginal cream that can block HIV transmission .
Lara Humberto Villegas , University of Monterrey and co -author of the study, says that HIV infects immune cells of its host, a protein called GP120 helps virus binding to cells.
He explains that the silver nanoparticles bind to the protein and block GP120 , which means that HIV can not infect immune cells.
Commenting on the creation , Lara Villegas says:
” Normally, the medicine used against the act of virus within the cell to prevent replication . This is a very different case , since the nanoparticle goes directly against HIV and no longer allows entry to the cell. ”
It is said that the cream has been tested in the laboratory using human tissue samples of cervical mucous membrane. It was found to effectively block HIV transmission .
Lara Villegas notes that the cream works in less than 1 minute after application and protects against transmission of the virus for up to 72 hours.
The researchers say that although the cream is for vaginal use , sexual partner also be protected against the virus.
The use of silver nanoparticles, the researchers created a vaginal cream that has proven effective in blocking HIV transmission .
However, Lara Villegas stressed that although there have been no negative side effects of silver nanoparticles so far, the team will conduct more research to be sure.
The next steps will be to test the cream on modified mice with human immune cells, before moving to clinical trials in humans.
The researchers note that the cream may also help protect against other sexually transmitted diseases such as human pappilloma virus ( HPV) which silver nanoparticles should be able to block this virus with the same process used to block infection HIV .
The team is also in the process of creating a diagnostic kit . The kit will do blood tests to predict whether a seropositive individual will respond to antiretroviral therapy.
They hope the kit will provide results within hours , and help doctors to ensure that their patients receive the best treatment for HIV.